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2018 ͊Ը߅Ҧ࢝
Gut microbiota (໑༸ഽ) Energy balance and metabolism
In response to acute HFD, LCR rats exhibited (ঐඎ̻ፅၾ˾ᑽ)
greater reductions in SCFA producers as well The elevated energy expenditure in the HCR
as their metagenomic potential for energy and
versus LCR indicates indicates differences in
carbohydrate metabolism.
efficiency.
(Panasevich et al., 2016; Pekkala et al., 2017)
HCR rats possess enhanced skeletal muscle
mitochondrial content and FAO, in addition to a
coordinated response for PPARδ and PGC-1α.
Rat Model (Thyfault & Morris, 2017; Overmyer et al., 2015)
Drs. Britton and Koch
Hepatic metabolism and disease Fat acids oxidation (FAO)
(ӿᛔ˾ᑽၾशष) (ইٴაःʷЪ͜)
The LCR present with negative health features The higher whole-body FAO in the HCR over
including metabolic syndrome, reduced heart the LCR is likely due to the greater skeletal
function, hepatic steatosis and disordered muscle and hepatic mitochondrial content and
sleep. FAO capacity witnessed in the HCR.
(Morris et al., 2014; Falegan et al., 2017) ( Overmyer et al., 2015; Morris et al., 2016)
ྡɓjყගഹΤ˂͛ൺӉঐɢ੶ࢮɽཽ̻ၽʘᏐ͜
ྡ˪Ը๕jර઼࿎eࢱᖵબ
ɧe ҦஔʘପุᏐ͜
༶ਗঐɢٙ৷Эೌڢ՟Ӕ፲ෂΪ९ձᐑྤΪ९ ν͛ݺ˙όձ༶ਗᇖ
ٙʝЪ͜dவԬΪ९ίᆽ֛त֛ࡈ༶ਗঐɢ˙ࠦٙ࿁্ᘠܘᗭПࠇfί
͉ɛၾӺྠඟהܔͭʘ৷ЭϞः༶ਗঐɢ̻ၽഐΥό࿔षא͛նಂʘ
ᜊʷ νྡɚהͪdઞী˂͛༶ਗঐɢၾ˾ᑽशष݊щϞᗫᑌd࿁ৰəϋჀ
ٙϼཽ̮ɰ০࿁ϼʷཽ˙ࠦආБጋd͉߰ӺᗇྼЭϞः༶ਗঐɢ̙ঐ݊˾
ᑽशषΚᎈΪɿʘɓd৷Ϟः༶ਗঐɢՈϞڭᚐ˸ʿַᇠЪ͜dϤϓ؈ਗ਼ঐ
Զ༶ਗ߅ኪאᔼኪჯਹהᏐ͜dЪމཫԣᔼኪʘӺਞϽf
ϤධӺϓ؈ʘҦஔପุᏐ͜d̙ʱЪɨΐᓃԸЪႭj
1. ༶ਗ͛ҦପุdપਗᘩҦ༶ਗ೯࢝ʘࠠࠅྼਕᏐ͜jϤ̻ၽ̙Զጜ፯ՈϞ
ʺ༶ਗڌତٙڭۜ९ҿf
2. ɾੰପุdᏐ͜ɾੰᗫӺjϤ̻ၽ̙Զ೯ପܝɾʿһϋ
ಂɾੰڮආၾशषཫԣอ͜f
3. ৷ᙧᔼኪପุdᏐ͜৷ᙧૄ໊ੰᗫӺjϤ̻ၽ̙ԶరҬַᇠϼʷٙ
ᗫᒟΪɿאཫԣϼʷཀٙЄЂݴ̰f
̻ၽʔස̙˸ઞী˂͛৷ЭϞः༶ਗঐɢίঐစʷɪٙᜊʷdɰ̙Ꮠ͜
˾ᑽशषeঐݺਗʔԑᗫषसeɾशषʿ৷ᙧᔼኪഃᙄᕚf̙˸ԶЪ
͊ԸίආБᐄቮᄣኒאʔΝ༶ਗᇖࠇࣛٙࠠࠅ္ܸᅺdɰ̙˸މၚ
ᔼᐕԶ̤ɓࡈ༆Ӕ˙ࣩdϤϓ؈ঐԶ༶ਗ߅ኪא፲ෂᔼኪהᏐ͜f
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